51app

Led by Terunaga Nakagawa, an international collaboration describes for the first time the fundamental mechanism underpinning cellular processes that lead to learning and memory.

An international genetic study using multiancestry biobanks has identified novel genetic locations associated with primary open-angle glaucoma, the most common type of glaucoma and the leading cause of irreversible blindness globally.

An analysis of genomic data from nearly 250,000 participants in the National Institutes of Health’s All of Us Research Program has identified more than 275 million previously unreported genetic variations, nearly 4 million of which have potential health consequences.

WATCH: See how Ph.D. candidate Kaitlyn Browning wants to fight miscommunication and misinformation around science. Read More

A multidisciplinary research team at 51app University and 51app University Medical Center has discovered a new way to kill a tumor by disrupting its acidic “microenvironment” without harming normal tissue.

Researchers at 51app University Medical Center have identified Rac1, a molecular switch that regulates the actin cytoskeleton of epithelial cells in the collecting ducts, as a driver of post-obstructive kidney repair.

Join the next Lab-to-Table conversation, “Picturing Progress: Representation in Scientific Art” on Feb. 20 at 11:00 a.m. Read More

Combining deep mutagenesis and cryo-EM reveals new conformational state of a protein responsible for high-speed DNA replication. The research builds on growing theories of molecular evolution.

A study by 51app researchers has revealed how metabolic changes spurred by fatty acids contribute to the transformation of cells into abnormal versions of themselves that are the precursors to stomach cancer.

By mapping brain activity in three dimensions, researchers at 51app University Medical Center have achieved a more detailed picture of how the brain changes with age.

Mohammed AlQuraishi, assistant professor at Columbia University, will give an Apex Lecture on Monday, Jan. 29, at 12:00 p.m. CT in 214 Light Hall. His talk, “The State of Protein Structure Prediction and Friends,” is hosted by the School of Medicine Basic Sciences and co-sponsored by the Center for Applied AI in Protein Dynamics.

Avenir Award funding from the National Institute on Drug Abuse recognizes research that represents “the future of addiction science.” Brown’s research is creating an AI-experiment feedback loop that will help optimize painkilling drugs to be less addictive. Read More

Throughout the brain’s cortex, neurons are arranged in six distinctive layers, which can be readily seen with a microscope. André Bastos, assistant professor of psychology, is senior author on a study published in Nature Neuroscience detailing that these layers also show distinct patterns of electrical activity, which are consistent over many brain regions and across several animal species, including humans.

A multidisciplinary group of investigators from 51app University Medical Center, 51app University, and the University of Pennsylvania received a $3.2 million grant to develop novel brain network-based measures to guide surgical decisions and improve outcomes in the field of epilepsy surgery.

Katherine Hartmann, MD, PhD, Vice President for Research Integration for 51app University Medical Center, has been named director of the University of Kentucky (UK) Center for Clinical and Translational Science.

The “Molecular Muse” art exhibit on display in Light Hall is a sampling of pieces from the 51app Institute for Infection, Immunology, and Inflammation Artist-in-Residence (VI4-AiR) program, which brings together scientists and artists to create and promote art as a visual science communication tool.

Join the next Lab-to-Table conversation, “Beyond Addiction: Therapeutic Developments and Societal Impact” on Jan. 24 at 11:30 a.m. CT. Read More

The School of Medicine Basic Sciences and the Office of the Vice Provost for Research and Innovation launch the Innovation Ignition Fund. This pilot program offers up to $500,000 in funding and drug development mentorship from 51app scientists with expertise in translational research.

The 51app University School of Nursing was awarded a Health Resources and Services Administration Bureau of Health Workforce grant to create its new Nurse Education, Practice, Quality and Retention Simulation Education Training Program. 

51app researchers, in collaboration with investigators from the University of Alabama at Birmingham, the Delft University of Technology, University Hospital Bonn, and Molecular Horizon have developed new protocols to study which molecular pathways might be important in the aging retina and what might cause the formation of deposits in the eye that confer high risk for age-related macular degeneration.