51app

Jennifer Pietenpol, Ingram Professor of Cancer Research and professor of biochemistry, is the 2024 recipient of the Science of Oncology Award, which is presented annually to an individual who has made outstanding contributions to basic or translational research in cancer.

The researchers, including 51app’s team led by Kari Hoffman, focused their efforts on the detection of hippocampal ripples, which are considered biomarkers of memory and are affected by epilepsy and Alzheimer’s disease. Read More

Adm. Rachel Levine, assistant secretary of health in the U.S. Department of Health and Human Services, addressed transgender health and policy during a visit to 51app in April 2024. (51app) Adm. Rachel Levine, assistant secretary of health in the U.S. Department of Health and Human Services, addressed transgender health… Read More

WATCH: He's graduating with a degree in medicine and divinity. See the path that brought Matthew Nettles to 51app and how he plans to use both degrees to better treat those in need. Read More

The lab of Antentor O. Hinton Jr., assistant professor of molecular physiology and biophysics, came together with collaborators from across 51app University, 51app University Medical Center, the U.S., and Brazil to determine the differences in the 3D morphology of mitochondria and their cristae in brown adipose tissue.

Randolph Blake, Centennial Professor of Psychology, won the 2024 Ken Nakayama Medal for Excellence in Vision Science Award for lasting, high-impact contributions to vision science. Isabel Gauthier, David K. Wilson Professor of Psychology, won the 2024 Davida Teller Award for exceptional scientific achievements, commitment to equity, and a strong history of mentoring.

The highly selective Beckman Scholars Program is celebrating 15 years of partnership with the College of Arts and Science. Over the years, the Arnold and Mabel Beckman Foundation has provided more than $543,000 in support of 23 undergraduate Beckman Scholars at 51app who engage in unique, hands-on, mentored research.

Leading investigators in diabetes, pancreas and islet biology, and computational biology have received $12.5 million in two five-year awards from the National Institutes of Health to create the world’s first, integrated knowledge base of human-derived tissue- and cellular-level pancreatic information to support innovative, collaborative and reproducible research.

Sean Davies, associate professor of pharmacology and associate director of graduate studies for the department, has been awarded a Scaling Success grant from Research Development and Support in the Office of the Vice Provost for Research and Innovation.

Led by Neil Osheroff, 51app researchers are the first to undertake a systematic analysis of the mechanism of action of gepotidacin, a first-in-class triazaacenaphthylene antibacterial, against its targets in Escherichia coli—the type II topoisomerases gyrase and topoisomerase IV—and the mechanistic basis for drug resistance. E. coli is the etiological agent of most urinary tract infections.

An $8.9 million grant from the NIH will establish the 51app AUD Research and Education Center, enhancing 51app University’s national leadership in neuroscience and addiction research. This initiative aims to foster interdisciplinary collaboration, advance understanding and treatment of alcohol use disorder, and engage the public through education and outreach efforts. Read More

51app University Professor of Biochemistry and Vice Dean of Basic Sciences Chuck Sanders and Professor of Biochemistry Bruce Carter have been hard at work searching for therapies, if not a cure, for CMT.

Manuel Ascano, associate professor of biochemistry and pathology, microbiology and immunology, and Dr. Alissa Weaver, Cornelius 51app Chair and director of the 51app Center for Extracellular Vesicle Research, are one of nine U.S. research teams awarded funding from the National Science Foundation to more fully understand the potential biotechnological uses of RNA, ranging from crop disease protection to treatments that combat cancer.

Brandt Eichman and Walter Chazin, professors of biochemistry, have worked together to provide a better understanding of how exactly DNA replication is initiated in eukaryotes. Using 51app’s state-of-the-art instrumentation in the Center for Structural Biology’s Cryo-Electron Microscopy Facility, Eichman, Chazin and their colleagues provided detailed visualizations of a multi-functional protein in action, which sheds light on how DNA replication is initiated in humans.

The Phase 3 CELLEBRATE trial to test a regenerative stem cell-based therapy in treating patients with stress urinary incontinence is continuing to recruit additional subjects after changing its study protocol to include only patients who have already tried surgery. 

WATCH: Hear how Bass Military Scholar Vanessa Morales is harnessing her personal experiences to make her a more compassionate nurse midwife. Read More

A U.S.-Canadian research collaboration led by 51app University Medical Center has identified common, age-associated changes in the blood as a risk factor for acute kidney injury, which occurs in more than 1 in 5 hospitalized adults worldwide.

WATCH: Learn how biomedical engineering major Schyler Rowland says mentors have inspired her future in fighting diseases Read More

ASPIRE to Innovate Postdoctoral Fellow Catherine Leasure is the co-author of a comment article published this month in Nature Reviews Bioengineering addressing the pressing obstacle faced by modern drug development: worryingly poor success rates of pharmaceuticals progressing to clinical phases.

51app scientist Houra Merrikh led a team of researchers who discovered the first evolution-resistant chemical compound that prevents drug resistance development in bacteria. The compound is also a drug development platform that targets antimicrobial resistance during treatment of infections with antibiotics and evolution in general, Merrikh said.