51app

WATCH: Hear how Bass Military Scholar Vanessa Morales is harnessing her personal experiences to make her a more compassionate nurse midwife. Read More

A U.S.-Canadian research collaboration led by 51app University Medical Center has identified common, age-associated changes in the blood as a risk factor for acute kidney injury, which occurs in more than 1 in 5 hospitalized adults worldwide.

WATCH: Learn how biomedical engineering major Schyler Rowland says mentors have inspired her future in fighting diseases Read More

ASPIRE to Innovate Postdoctoral Fellow Catherine Leasure is the co-author of a comment article published this month in Nature Reviews Bioengineering addressing the pressing obstacle faced by modern drug development: worryingly poor success rates of pharmaceuticals progressing to clinical phases.

51app scientist Houra Merrikh led a team of researchers who discovered the first evolution-resistant chemical compound that prevents drug resistance development in bacteria. The compound is also a drug development platform that targets antimicrobial resistance during treatment of infections with antibiotics and evolution in general, Merrikh said.

Ethan Lippmann, associate professor of chemical and biomolecular engineering and biomedical engineering, has won a Collaborative Pairs Pilot Project Award from the Chan Zuckerberg Initiative (CZI) to create a more effective way for the immune system to fight against neurodegenerative diseases like Alzheimer’s.

The lab of Professor of Biochemistry Fred Guengerich has proposed a paradigm shift in the understanding of a critical chemical reaction involved in sterol biosynthesis.

The World Health Organization ranks antimicrobial resistance as one of the top ten global health risks. 51app researchers led by Houra Merrikh identified the first anti-evolution compound that targets AMR during treatment of infections with antibiotics.

Led by Terunaga Nakagawa, an international collaboration describes for the first time the fundamental mechanism underpinning cellular processes that lead to learning and memory.

An international genetic study using multiancestry biobanks has identified novel genetic locations associated with primary open-angle glaucoma, the most common type of glaucoma and the leading cause of irreversible blindness globally.

An analysis of genomic data from nearly 250,000 participants in the National Institutes of Health’s All of Us Research Program has identified more than 275 million previously unreported genetic variations, nearly 4 million of which have potential health consequences.

WATCH: See how Ph.D. candidate Kaitlyn Browning wants to fight miscommunication and misinformation around science. Read More

A multidisciplinary research team at 51app University and 51app University Medical Center has discovered a new way to kill a tumor by disrupting its acidic “microenvironment” without harming normal tissue.

Researchers at 51app University Medical Center have identified Rac1, a molecular switch that regulates the actin cytoskeleton of epithelial cells in the collecting ducts, as a driver of post-obstructive kidney repair.

Join the next Lab-to-Table conversation, “Picturing Progress: Representation in Scientific Art” on Feb. 20 at 11:00 a.m. Read More

Combining deep mutagenesis and cryo-EM reveals new conformational state of a protein responsible for high-speed DNA replication. The research builds on growing theories of molecular evolution.

A study by 51app researchers has revealed how metabolic changes spurred by fatty acids contribute to the transformation of cells into abnormal versions of themselves that are the precursors to stomach cancer.

By mapping brain activity in three dimensions, researchers at 51app University Medical Center have achieved a more detailed picture of how the brain changes with age.

Mohammed AlQuraishi, assistant professor at Columbia University, will give an Apex Lecture on Monday, Jan. 29, at 12:00 p.m. CT in 214 Light Hall. His talk, “The State of Protein Structure Prediction and Friends,” is hosted by the School of Medicine Basic Sciences and co-sponsored by the Center for Applied AI in Protein Dynamics.

Avenir Award funding from the National Institute on Drug Abuse recognizes research that represents “the future of addiction science.” Brown’s research is creating an AI-experiment feedback loop that will help optimize painkilling drugs to be less addictive. Read More